Dr rudolf jaenisch biography
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Rudolf Jaenisch
German biologist
Rudolf Jaenisch (born on April 22, 1942) is a professor of biology at MIT and a founding member of the Whitehead Institute for Biomedical Research.[1] He is a pioneer of transgenic science, in which an animal’s genetic makeup is altered.
Jaenisch has focused on creating genetically modified mice to study cancer, epigenetic reprogramming and neurological diseases.[2][3][4]
Research
Jaenisch's first breakthrough occurred in 1974, when he and Beatrice Mintz showed that foreign DNA could be integrated into the DNA of early mouse embryos[5] They injected retrovirus DNA into early mouse embryos and showed that leukemia DNA sequences had integrated into the mouse genome and also into that of its offspring.
These mice were the first transgenic mammals in history.[6]
His current research focuses on the epigenetic regulation of gene expression,[7] which has led to major advances i
